University of Pittsburgh


Organ System Pathophysiology


January 7, 2019-January 18, 2019
10 half days

Course Director
Roy E. Smith, MD
Department of Medicine

Course Description

This course builds on concepts established during immunology and pathology in the consideration of the impact of diseases of the circulating elements of blood.

The goals of the course are:

  1. to understand the organization and function of the blood forming organs, the structure and functions of circulating elements and the basics of hematology.
  2. to learn of common hematologic disorders, their etiology, defining characteristics, diagnosis and treatment.
  3. to especially focus on benign and malignant disorders of the white blood cells with respect to diagnosis and etiology.
  4. to introduce students to the different laboratory techniques used in hematology.

The 30 faculty are from 7 departments: Hematology Oncology; Medicine; Molecular Genetics and Biochemistry (Human Genetics Program); Pathology (Division of Hematopathology); Pediatrics; Pharmacology; Radiation Oncology.

Educational Methods


Lectures Case-based small groups Quizzes Virtual cases
Workshops Peer instruction Team-based teaching    



Evaluation for this course is based on a final examination that is multiple-choice and on the performance on the quizzes.

Grading: This course comprises 17% of the grade for the Organ Systems Pathophysiology Block, Section 3. Grading for the block is Satisfactory or Unsatisfactory.

Faculty Note

Margaret Ragni, MD, is a recipient of the Kenneth E. Schuit Award, recognizing the Dean’s Master Educators.