Course Director and Block Lead
Martin Schmidt, PhD
Professor, Department of Microbiology and Molecular Genetics
mcs2@pitt.edu
Course Description
Keystone Fundamentals (KF; MED 5201) serves as the introduction to foundational science and integrates the core disciplines of anatomy, histology, immunology, genetics, pharmacology, biochemistry, pathology, hematology and microbiology into a case-based, clinically-relevant curriculum. The course will explore the body and its functions to prepare students for Organ Systems ahead of Clerkships.
Course Objectives
- Describe the major metabolic pathways and understand how they are regulated to maintain homeostasis
- Describe the organization, replication, and expression of the human genome, and the impact of sequence variants on human diversity and health.
- Assess normal and disease states at gross anatomical and histological levels
- Describe pathogenesis and etiology of infection
- Describe the principles of immunology and the mechanisms of tolerance
- Describe the molecular basis for the actions of pharmaceuticals and the factors controlling their absorption, distribution, metabolism and excretion.
- Describe the components of blood and differentiate between various hematologic disorders using the complete blood count and coagulation tests
- Apply basic science knowledge to specific clinical cases
Educational Methods
- Independent learning modules (pre-recorded)
- Interactive small group activities in a highly supportive environment
- Medium group or large group learning
- Review sessions
- Formative and Summative assessments
- Visual Human Atlas Laboratory (histology, pathology, and radiology, etc.)
Assessment
Assessment for this phase of the course segment is based on 2 cumulative Summative exams (midpoint and final).
Requests for excused absences should be submitted via Elentra. Unexcused absences may result in grading penalties as outlined in the Policy on Absence and Attendance.